ABO blood group predictions are brand new, and still under development. We're rolling it out to you so we can see how it performs on real data. All conclusions are still greatly limited by the general lack of phased data, the lack of genotyping at all of the necessary snps, and other factors.
best guess:ABO blood type unknown-
rs590787(C;C) rs8176719(I;D) rs8176719(G;G) rs8176746(C;C) rs8176747(C;C)rs8176719(G;G) indicates you are not type-O
rs8176746(C;C) and rs8176747(C;C) suggests you are not type-A. rs8176746(C;C) and rs8176747(C;C) suggests you are not type-B
rs590787(C;C) indicates rh-
But the ABO system is quite limited
Blood, you see, doesn't just come in types A, B, AB, and O. The "positive" or "negative?" Nope. In fact, let's get all the way into the weeds: Scientists have since discovered over 300 proteins that contribute to blood type. The AB+ on your blood donor card? Yeah, that's a massive oversimplification... read more at Beyond Blood Type: Genomics Can Show What You're Really Made Of
or
It would be straightforward if we all had the same blood. But we don't. On the surface of every one of our red blood cells, we have up to 342 antigens - molecules capable of triggering the production of specialised proteins called antibodies. It is the presence or absence of particular antigens that determines someone's blood type.
Some 160 of the 342 blood group antigens are 'high-prevalence', which means that they are found on the red blood cells of most people. If you lack an antigen that 99 per cent of people in the world are positive for, then your blood is considered rare. If you lack one that 99.99 per cent of people are positive for, then you have very rare blood.
If a particular high-prevalence antigen is missing from your red blood cells, then you are 'negative' for that blood group. If you receive blood from a 'positive' donor, then your own antibodies may react with the incompatible donor blood cells, triggering a further response from the immune system. These transfusion reactions can be lethal. Read more at The man with the golden blood.
Known ABO SNPs
Index | Gene | SNP | Geno | Repute | Magnitude | Summary |
---|---|---|---|---|---|---|
1 | rs7466519 | not tested | ||||
2 | ABO | rs8176750 | (I;D) | |||
3 | rs56202119 | not tested | ||||
4 | ABO | i4000505 | (G;G) | Good | 0.0 | |
5 | rs56231718 | not tested | ||||
6 | rs55788852 | not tested | ||||
7 | rs55927860 | not tested | ||||
8 | ABO | rs8176749 | (G;G) | 0.0 | ||
9 | rs56190619 | not tested | ||||
10 | rs55783488 | not tested | ||||
11 | rs56355240 | not tested | ||||
12 | ABO | i4000504 | (C;C) | 0.0 | ||
13 | rs56409303 | not tested | ||||
14 | rs55805279 | not tested | ||||
15 | rs56106480 | not tested | ||||
16 | ABO | rs8176747 | (C;C) | |||
17 | ABO | rs41302905 | (C;C) | Good | 0.0 | common in complete genomics |
18 | ABO | rs8176746 | (C;C) | 0.0 | ||
19 | rs8176745 | not tested | ||||
20 | rs55951833 | not tested | ||||
21 | ABO | rs8176743 | (G;G) | 0.0 | ||
22 | i5007173 | not tested | ||||
23 | rs55739900 | not tested | ||||
24 | rs56116432 | not tested | ||||
25 | rs56031507 | not tested | ||||
26 | rs8176741 | not tested | ||||
27 | rs56408700 | not tested | ||||
28 | ABO | rs8176740 | (A;T) | |||
29 | ABO | rs8176740 | (A;A) | |||
30 | rs55827808 | not tested | ||||
31 | rs8176739 | not tested | ||||
32 | rs56223957 | not tested | ||||
33 | rs56189011 | not tested | ||||
34 | rs56089890 | not tested | ||||
35 | rs55727303 | not tested | ||||
36 | ABO | rs7853989 | (G;G) | Not blood group B | ||
37 | rs55964869 | not tested | ||||
38 | rs55756402 | not tested | ||||
39 | i5007171 | not tested | ||||
40 | ABO | rs1053878 | (C;T) | |||
41 | rs55658842 | not tested | ||||
42 | rs7873522 | not tested | ||||
43 | rs8176732 | not tested | ||||
44 | ABO | rs2073824 | (A;G) | |||
45 | rs8176722 | not tested | ||||
46 | rs8176721 | not tested | ||||
47 | rs8176720 | not tested | ||||
48 | ABO | rs8176719 | (I;D) | |||
49 | ABO | rs8176719 | (G;G) | most likely to be of blood type A, B or AB | ||
50 | rs56231711 | not tested | ||||
51 | rs8176717 | not tested | ||||
52 | ABO | rs512770 | (A;G) | |||
53 | rs641959 | not tested | ||||
54 | rs514708 | not tested | ||||
55 | rs55958637 | not tested | ||||
56 | rs549446 | not tested | ||||
57 | ABO | rs8176704 | (A;G) | |||
58 | ABO | rs574347 | (C;T) | |||
59 | rs688976 | not tested | ||||
60 | ABO | rs687289 | (A;G) | |||
61 | ABO | rs2073828 | (G;G) | |||
62 | rs55876802 | not tested | ||||
63 | ABO | rs8176694 | (A;G) | |||
64 | rs672316 | not tested | ||||
65 | ABO | rs657152 | (A;C) | |||
66 | rs8176682 | not tested | ||||
67 | rs474279 | not tested | ||||
68 | ABO | rs500498 | (CC;G) | |||
69 | ABO | rs500498 | (C;T) | |||
70 | ABO | rs505922 | (C;GA) | |||
71 | ABO | rs505922 | (C;T) | Bad | 1.2x risk of pancreatic cancer | |
72 | rs507666 | not tested | ||||
73 | ABO | rs630014 | (C;T) |
Index | Gene | SNP | Geno | Repute | Magnitude | Summary |
---|---|---|---|---|---|---|
1 | ABO | rs1053878 | (C;T) | |||
2 | ABO | rs2073824 | (A;G) | |||
3 | ABO | rs2073828 | (G;G) | |||
4 | rs2519093 | not tested | ||||
5 | ABO | rs41302905 | (C;C) | Good | 0.0 | common in complete genomics |
6 | ABO | rs500498 | (CC;G) | |||
7 | ABO | rs500498 | (C;T) | |||
8 | ABO | rs505922 | (C;GA) | |||
9 | ABO | rs505922 | (C;T) | Bad | 1.2x risk of pancreatic cancer | |
10 | rs507666 | not tested | ||||
11 | ABO | rs512770 | (A;G) | |||
12 | ABO | rs514659 | (A;C) | |||
13 | rs55722397 | not tested | ||||
14 | rs55964869 | not tested | ||||
15 | rs56392308 | not tested | ||||
16 | ABO | rs574347 | (C;T) | |||
17 | ABO | rs612169 | (A;G) | |||
18 | ABO | rs630014 | (C;T) | |||
19 | ABO | rs643434 | (A;G) | |||
20 | ABO | rs644234 | (G;T) | |||
21 | ABO | rs657152 | (A;C) | |||
22 | ABO | rs687289 | (A;G) | |||
23 | ABO | rs687621 | (A;G) | |||
24 | ABO | rs687621 | (C;G) | |||
25 | ABO | rs7853989 | (G;G) | Not blood group B | ||
26 | ABO | rs8176694 | (A;G) | |||
27 | ABO | rs8176704 | (A;G) | |||
28 | ABO | rs8176719 | (I;D) | |||
29 | ABO | rs8176719 | (G;G) | most likely to be of blood type A, B or AB | ||
30 | rs8176720 | not tested | ||||
31 | rs8176722 | not tested | ||||
32 | ABO | rs8176740 | (A;T) | |||
33 | ABO | rs8176740 | (A;A) | |||
34 | rs8176741 | not tested | ||||
35 | ABO | rs8176743 | (G;G) | 0.0 | ||
36 | ABO | rs8176746 | (C;C) | 0.0 | ||
37 | ABO | rs8176747 | (C;C) | |||
38 | ABO | rs8176749 | (G;G) | 0.0 | ||
39 | ABO | rs8176750 | (I;D) |
Index | Gene | SNP | Geno | Repute | Magnitude | Summary |
---|---|---|---|---|---|---|
1 | ABCG2 | rs2231142 | (C;C) | Good | 0.0 | normal |
2 | rs72552713 | not tested | ||||
3 | ANKK1 | rs1800497 | (C;C) | Good | 3.0 | Normal (A2/A2): Better avoidance of errors. Normal OCD risk, normal Tardive Diskinesia risk, lower ADHD risk. Less Alcohol dependence. Higher risk of Postoperative Nausea. Lower obesity. Bupropion is ... |
4 | rs429358 | not tested | ||||
5 | APOE | rs7412 | (C;C) | Bad | 1.1 | more likely to gain weight if taking olanzapine |
6 | COMT | rs4680 | (A;A) | Good | 2.5 | (worrier) advantage in memory and attention tasks |
7 | CYP1A2 | rs12720461 | (C;C) | Good | 0.0 | normal |
8 | rs2069514 | not tested | ||||
9 | rs35694136 | not tested | ||||
10 | rs56107638 | not tested | ||||
11 | CYP1A2 | rs762551 | (A;A) | 2.0 | Fast Caffeine Metabolizer. | |
12 | rs12721655 | not tested | ||||
13 | CYP2B6 | rs2279343 | (A;A) | Good | 0.0 | common in clinvar |
14 | CYP2B6 | rs28399499 | (T;T) | Good | 0.0 | common in complete genomics |
15 | CYP2B6 | rs3211371 | (C;T) | |||
16 | CYP2B6 | rs34097093 | (C;C) | Good | 0.0 | common in complete genomics |
17 | CYP2B6 | rs34223104 | (T;T) | Good | 0.0 | common in complete genomics |
18 | CYP2B6 | rs35303484 | (A;A) | Good | 0.0 | common/normal |
19 | CYP2B6 | rs3745274 | (G;G) | Good | 0.0 | common in clinvar |
20 | CYP2C19 | rs12248560 | (G;T) | |||
21 | CYP2C19 | rs12248560 | (C;T) | 2.0 | CYP2C19*17 ultra fast metabolizer; drug metabolism effects; also 0.77x decreased breast cancer risk | |
22 | CYP2C19 | rs17878459 | (G;G) | Good | 0.0 | normal |
23 | CYP2C19 | rs17884712 | (G;G) | Good | 0.0 | normal |
24 | rs17885098 | not tested | ||||
25 | rs17886522 | not tested | ||||
26 | CYP2C19 | rs28399504 | (A;A) | Good | 0.0 | normal |
27 | rs3758580 | not tested | ||||
28 | CYP2C19 | rs41291556 | (T;T) | Good | 0.0 | normal |
29 | CYP2C19 | rs4244285 | (G;G) | Good | 0.0 | normal |
30 | CYP2C19 | rs4986893 | (G;G) | Good | 0.0 | normal |
31 | rs55640102 | not tested | ||||
32 | rs56337013 | not tested | ||||
33 | CYP2C19 | rs6413438 | (C;C) | Good | 0.0 | normal |
34 | rs72552267 | not tested | ||||
35 | rs72558186 | not tested | ||||
36 | CYP2C9 | rs1057910 | (A;C) | Bad | 2.5 | CYP2C9*3 carrier; average 40% reduction in warfarin metabolism |
37 | CYP2C9 | rs1057910 | (C;T) | |||
38 | CYP2C9 | rs1799853 | (C;C) | Good | 0.1 | normal; no change in warfarin metabolism |
39 | CYP2C9 | rs28371685 | (C;C) | Good | 0.0 | normal |
40 | CYP2C9 | rs28371686 | (C;C) | Good | 0.0 | normal |
41 | rs56165452 | not tested | ||||
42 | rs72558187 | not tested | ||||
43 | rs72558188 | not tested | ||||
44 | rs72558190 | not tested | ||||
45 | CYP2C9 | rs7900194 | (G;G) | Good | 0.0 | normal |
46 | CYP2C9 | rs7900194 | (G;G) | Good | 0.0 | normal |
47 | CYP2C9 | rs9332130 | (A;A) | Good | 0.0 | normal |
48 | CYP2C9 | rs9332131 | (I;I) | Good | 0.0 | normal |
49 | CYP2C9 | rs9332239 | (C;C) | Good | 0.0 | normal |
50 | CYP2D6 | rs1065852 | (C;C) | Good | 0.0 | normal |
51 | CYP2D6 | rs1080985 | (C;C) | 0.1 | a common variant | |
52 | rs147960066 | not tested | ||||
53 | rs16947 | not tested | ||||
54 | CYP2D6 | rs28371706 | (C;C) | Good | 0.0 | normal |
55 | rs28371720 | not tested | ||||
56 | CYP2D6 | rs28371725 | (A;A) | CYP2D6*41 homozygote | ||
57 | CYP2D6 | rs28371725 | (A;G) | carrier of one CYP2D6*41 allele | ||
58 | rs35742686 | not tested | ||||
59 | rs3892097 | not tested | ||||
60 | CYP2D6 | rs5030655 | (I;I) | Good | 0.0 | normal |
61 | CYP2D6 | rs5030862 | (G;G) | Good | 0.0 | normal |
62 | rs5030863 | not tested | ||||
63 | rs5030865 | not tested | ||||
64 | rs5030865 | not tested | ||||
65 | CYP2D6 | rs5030867 | (A;A) | Good | 0.0 | normal |
66 | rs59421388 | not tested | ||||
67 | rs72549349 | not tested | ||||
68 | rs72549351 | not tested | ||||
69 | rs72549353 | not tested | ||||
70 | rs72549354 | not tested | ||||
71 | rs72549357 | not tested | ||||
72 | rs769258 | not tested | ||||
73 | rs12721629 | not tested | ||||
74 | CYP3A | rs2740574 | (A;A) | Good | 0.0 | normal |
75 | rs35599367 | not tested | ||||
76 | rs4646438 | not tested | ||||
77 | CYP3A4 | rs4986910 | (T;T) | Good | 0.0 | normal |
78 | CYP3A4 | rs4987161 | (T;T) | Good | 0.0 | normal |
79 | rs55785340 | not tested | ||||
80 | CYP3A5 | rs10264272 | (C;C) | Good | 0.0 | normal |
81 | rs15524 | not tested | ||||
82 | CYP3A5 | rs28365083 | (C;C) | Good | 0.0 | normal |
83 | rs28383468 | not tested | ||||
84 | CYP3A5 | rs28383479 | (G;G) | Good | 0.0 | normal |
85 | CYP3A5 | rs41279854 | (A;A) | Good | 0.0 | normal |
86 | rs41303343 | not tested | ||||
87 | rs55817950 | not tested | ||||
88 | rs55965422 | not tested | ||||
89 | CYP3A5 | rs776746 | (G;G) | Bad | 2.5 | CYP3A5*3 homozygote; CYP3A5 non-expressor |
90 | rs1799963 | not tested | ||||
91 | F5 | rs6025 | (G;G) | Good | 0.0 | normal/common |
92 | MTHFR | rs1801131 | (A;C) | Bad | 2.1 | Possibly impaired folate metabolism |
93 | MTHFR | rs1801133 | (C;C) | Good | 0.0 | Common genotype: normal homocysteine levels |
94 | OPRM1 | rs1799971 | (A;A) | Good | 0.0 | normal |
95 | SLCO1B1 | rs2306283 | (C;C) | |||
96 | SLCO1B1 | rs4149056 | (C;T) | Bad | 2.1 | reduced breakdown of some drugs; 5x increased myopathy risk for statin users |
97 | rs55737008 | not tested | ||||
98 | rs56061388 | not tested | ||||
99 | rs56101265 | not tested | ||||
100 | rs59502379 | not tested | ||||
101 | rs72559745 | not tested | ||||
102 | UGT2B15 | rs1902023 | (G;T) | |||
103 | VKORC1 | rs8050894 | (G;G) | 2.1 | warfarin resistance (~6.5 mg/day) | |
104 | VKORC1 | rs9923231 | (T;T) | 2.1 | reduced warfarin dose if treated for VTE | |
105 | VKORC1 | rs9934438 | (A;A) | Bad | 2.5 | coumadin resistance |